MIRD Primer 2022, 医療内部被ばく 教本 2022, 9780932004031, 978-0-932004-03-1
Description
Absorbed dose and related quantities are the key predictors of the beneficial (therapeutic) effects of radiation and of the risk and/or severity of its adverse effects. The estimation of such dosimetric parameters is challenging, however, particularly for radiopharmaceuticals. Richly illustrated and thoroughly referenced, the MIRD Primer 2022: A Complete Guide to Radiopharmaceutical Dosimetry is a comprehensive, state-of-the-art guide to radiopharmaceutical dosimetry that reflects the dramatic evolution of the field of nuclear medicine, including molecular imaging and, increasingly, radiopharmaceutical therapy.
The MIRD Primer 2022 serves as a foundation for nuclear medicine and other medical professionals who require a working knowledge of internal radionuclide dosimetry and its radiobiological implications-without having to delve too deeply into the underlying mathematics. an authoritative reference on the latest, complete mathematical formulation of the MIRD schema for those seeking a more rigorous understanding of internal dosimetry. an invaluable teaching tool, with a large number and wide variety of clinically relevant calculational examples. The historical development of internal dosimetry, uncertainty in dose and radiation risk estimation, currently available dosimetry software, and regulatory aspects of radiopharmaceutical dosimetry are all addressed as well. Exhaustively revised and greatly expanded from the original MIRD Primer, this book addresses the important distinction between dosimetry for risk assessment in diagnostic imaging versus dosimetry for treatment efficacy and toxicity evaluation in the setting of therapy, including guidance on treatment planning.